Ingredients, Formulation and Finishing
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Roquette During the tableting of orodispersible tablets (ODT), capping was observed by the client on the M2i industrial machine. Despite various trials to adjust the compression settings, the client could not solve the capping issue. Therefore, a study has been performed in order to understand the capping issue - in particular, whether it could be related to potential batch-to-batch particle size variability, or to non-optimal tableting settings.
LB Bohle The L. B. Bohle Maschinen + Verfahren GmbH product range of proven fluid bed systems extends from the smallest Bohle Fluid Bed System BFS 3 through to the “flag ship“ BFS 480. At this year’s ACHEMA, the granulation and coating specialists will be presenting the further development of the “bestseller” in the medium range – the BFS 240.
LB Bohle Continuous processes are strongly increasing in the solids pharmaceutical industry.
The new BRC 100 dry granulator closes a gap in the range offered by L.B. Maschinen
+ Verfahren at ACHEMA 2012. Customers are now able to undertake all granulation
processes with machines from Ennigerloh. This unique combination of the most
common granulation processes (high-speed blender, fluid bed, single-pot and twinscrew
granulation) makes it possible to meet customers’ requirements more
specifically and professionally than before. “The dry granulator BRC 100 marks a
further milestone which fits our philosophy of staying on top of the market," said
entrepreneur Lorenz Bohle.
Hielscher Ultrasonics Ultrasonic Milling and Dispersing in the Nano Technology Sector.
The dispersing and deagglomeration of solids into liquids is an important application of
ultrasonic devices. If powders are wetted, the individual particles build agglomerates and are
held together by attraction forces of various physical and chemical nature, including van der
Waals forces and liquid surface tension. This effect is stronger for higher viscosity liquids,
such as polymers or resins. The attraction forces must be overcome on order to
deagglomerate and disperse the particles into liquid media. An even dispersion and
deagglomeration is important to use the full potential of the particles. Especially nano
particles offer extraordinary characteristics, which can only be exploited in highly even
BENEO-Palatinit GmbH In 2005 BENEO-Palatinit launched its multifunctional bulk excipient range under the brand name galenIQ™. Now, the pharmaceutical grade of isomalt has found its way into direct compressed tablets and sachets for direct oral application at first. The highly functional filler-binder is available in various particle modifications and different solubilities.