SPOT LIGHT

Wel-Screen is driven by research-active chemists, molecular biologists, and biochemists who understand the importance of timely, reliable data to get your trial across the finishing line.

Using best-in-class technology and techniques, our experts work side by side with scientists in the pharma industry to provide critical, cost-effective, and efficient chemical testing to support every stage of drug discovery and development.

Our range of specialist analyses provide critical details on the authenticity, composition, origin, identity, purity, and safety of samples with fast turnaround and rapid processing guaranteed.

Wel-Screen’s strength lies in the range of services it provides. Multiple analyses can be carried out simultaneously using just a single sample. By providing a broad range of services all under one roof, Wel-Screen can help scientists and researchers in the pharma industry to increase efficiency, reduce costs, and accelerate breakthroughs.

We perform high-quality SEM services for scientists working in pharmaceutical science, materials science, biotechnology, biochemistry, and gemology. Our analyses provide crucial information on the surface topography and composition of samples. Our tests are ideal for scientists working in a huge range of fields, from research involving nanoparticles, microparticles, materials science, and polymers, or more broadly with fundamental materials.

Our DSC capabilities are used by pharma researchers and scientists to measure thermal and physico-chemical properties of chemical compounds, proteins, and other biomolecules. Our detailed and accurate DSC tests are a cost-effective way to determine properties such as glass transition temperature, melting and boiling points, phase changes, or thermal-oxidative stability. This information is critical for checking the purity of samples, qualitative analysis, or the detection of polymorphism.

GC-MS is critical during drug discovery procedures in order to ascertain the molecular weight, structure, and empirical formula of a given sample. GC-MS is sensitive and precise – offering the highest levels of accuracy required for material testing, identification, and certification. GC-MS is ideal for analysing volatile compounds with low-detection limits. With our streamlined workflow and state-of-the-art facilities, we’re able to rapidly process samples, giving you certainty in your sample and confidence in your products. Similar to liquid chromatography-mass spectroscopy (LC-MS) services (see below), GC-MS is used by researchers working in pharmaceutical, environmental, or food and beverage science. It can also be used during the early stages of drug discovery.

Infrared spectroscopy offers details on the chemical composition and structure of a sample. Using state-of-theart Shimadzu instrumentation, we obtain high-resolution and high-sensitivity data for a variety of non-destructive measurement or structural analysis applications, such high-fidelity infrared analysis provides critical quantitative and qualitative high-resolution spectral data quickly and accurately. This analysis is useful during the synthesis and the purification of active pharmaceutical ingredients (APIs) to determine sample purity.

LC-MS is often used during the early drug discovery procedure, as well as in metabolism studies. Our costeffective LC-MS test provides detailed, accurate information on the molecular weight, structure, and empirical formulae of specific sample components. LC-MS is a critical test for scientists who want accurate information on composition and purity when working with organic compounds, solvents, or biomolecules.

Our lyophilisation service enables pharma researchers and scientists to freeze-dry their samples or products through a low-temperature dehydration process, thus vastly improving their storage life. We recognise that you may need to lyophilise samples for different reasons, including making them stable or for sample analysis. If required, we can use differential scanning calorimetry to design and develop successful lyophilisation cycles for particularly unstable or thermally sensitive preparations. Whatever your specific lyophilisation needs, we can provide a bespoke service shaped around your research requirements.

NMR can be used by researchers and scientists for quality control, to identify an unknown compound in research, or to determine the content and the purity of a sample. NMR provides critical details on the chemical structure of a compound and is suitable for those studying APIs, fine chemicals, and natural products.

The Orbitrap ion trap mass-analyser is used to provide researchers with cost-effective analysis of organic compounds and biomolecules. Researchers working in the various stages of drug discovery, including proteomics, or the synthesis of small molecular weight compounds, use Orbitrap to identify organic compounds and high-molecularweight biomolecules – it is especially useful for analysing complex protein mixtures. Orbitrap data can be applied in multiple fields: the drug discovery pipeline, metabolism studies, in pharmacokinetic and pharmacodynamics analyses, and in preclinical development.