CONTENTS
Winter 2025
Imaging and Sensing
8. How imaging flow cytometry is transforming cell and protein therapy Advancements in imaging flow cytometry have improved the detection of particles in pharmaceutical formulations and helped provide insights into how these protein-based therapeutics work.
Discovery and Development
11. From passive polymers to active platforms: the nanotech evolution of hydrogels
Nanotechnology has unlocked a new generation of hydrogels that can be tuned for specific clinical demands. From degradation kinetics to drug release and mechanical resilience, nanoscale control is transforming hydrogels from passive wound dressings into active, minimally invasive platforms for joint restoration, tissue regeneration and targeted therapeutics.
14. Closing the actionability gap: spatial cell sorting advances drug discovery and translational research
Mapping disease cells in tissue is essential, but extracting and analysing them is what advances drug discovery. Spatial cell sorting enables physical isolation of individual cells for comprehensive multi-omics profiling – bridging the gap between tissue visualisation and functional validation.
Digital
18. Building fine-tuning capabilities for co-folding models in pharmaceutical research
What are co-folding models and how is their use transforming drug development?
21. The new risk equation: balancing safety, speed and innovation in digital pharma
How can pharma companies improve their digital systems while maintaining regulatory compliance, and ensure the two teams work together cohesively?
24. Making sense of your scientific archive: how RAG helps biotechs do more with less
How is retrieval-augmented generation aiding smaller biotechs in collating and utilising disparate data systems?
Manufacturing
SPOT LIGHT
28. X-ray CT for tablets: a powerful non-destructive tool for tablet characterisation
How is X-ray CT being used to ensure quality in tabletting?
32. Sustainable and scalable approaches to peptide manufacturing
Process innovations provide opportunities to reduce environmental impact while improving efficiency and product quality.
35. Semantic layering: the technology reshaping pharma data architecture
How is semantic layering technology addressing significant efficiency gaps, creating the infrastructure for more efficient manufacturing operations?
Lab Design
38. Drug discovery’s weakest link? Why synthesis is the critical bottleneck in the age of AI
How is artificial intelligence being utilised in labs to synthesise design and workloads?
42. Labs that think: how intelligent design is shaping the future of pharma R&D
How are emerging design principles like operational insight, molecular infrastructure and human-centred design reshaping safety, agility and performance across the life sciences landscape?
45. Advancing fluid management in labs with automated small-volume filling
How can the introduction of automation in fluid management systems improve biopharma manufacturing?
48. Designing for the next generation of pharma labs
How are modern pharma labs being designed with practicality and connectivity to ensure streamlined processes and happy staff?
Regulars
5. Eds Desk
While the world slows down for the holidays, the pharma industry continues at pace into 2026!
6. Product News
IPT highlights some of the most recent exciting advancements in pharmaceutical manufacturing.
50. Events
A collation of the top Pharma events for Winter 2025!
Index of Advertisers
27. INTERCROY
IBC. EHP Awards
OBC. Natoli
EXECUTIVE DIRECTOR
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Karl Equi
GROUP MANAGING EDITOR
PMGroup Worldwide Ltd
Iona Everson
EDITORS
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Yasmin Nolan
SALES
Eliot Haynes
DESIGN
Peter May
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Innovations in Pharmaceutical Technology (ISSN: 1471-7204, USPS No: 025082) is published four times a year – March, June, September, and December – by Samedan Ltd.
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