Spatial biology is moving from research curiosity to clinical reality – and the results are already changing how we understand and treat disease. The key to unlocking its full potential lies in automated, reproducible, end-to-end workflows that turn tissue complexity into clear, actionable decisions.

14 De-risking gene therapy development through efficient stress testing of viral vectors

Could next-generation analytical technologies unlock faster, more informative stress testing for viral vectors?

Discovery and Development

17 Implementing iPSC-derived models in drug development workflows

As regulatory agencies encourage the adoption of new approach methodologies, pharmaceutical developers are increasingly exploring human iPSC-derived models to improve translational predictivity.

20 Cell-based workflows: the missing data layer in AI-enabled drug discovery

Can artificial intelligence truly transform drug discovery without equally transforming the biology and data that underpin it?

24 Fit-for-purpose measurement in drug development: aligning analytics with decision-making across workflows

Analytical measurement in drug development spans multiple attributes, from concentration and binding to quality, impurities, and function.

28 Starting material: the forgotten building block of CGT manufacturing

Before accepting a vial, bag or tissue sample, cell and gene therapy developers should ask three questions: is donor consent fit for purpose, was the right testing performed?

31 From concept to clinic – partnering to scale up cell and gene therapies

How can the industry bridge the gap between cell and gene therapy innovation and reliable large-scale manufacturing?

34 How human tissue models could transform preclinical drug development

Animal testing in drug development is facing growing pressure as scientists and regulators adopt more human-relevant alternatives.

Manufacturing

37 Integrated dissolution-absorption testing: a strategic imperative for establishing generic drug bioequivalence

In the fast-paced, competitive world of generics manufacturing, processes such as integrated-dissolution-absorption testing can mean the difference between firstto-market and obscurity.

40 Resilience in pharmaceutical manufacturing: what connected operations now require

Pharmaceutical manufacturers are rethinking operational resilience as connected systems, automation and infrastructure dependencies play a larger role in production.

44 Scaling oligonucleotide manufacturing for the cardiometabolic era

A wave of small interfering RNA therapeutics targeting prevalent cardiometabolic diseases is anticipated to drive active pharmaceutical ingredients demand beyond the scale that existing manufacturing models were designed to support.

48 A new kind of blockbuster: could autonomous manufacturing transform pharma?

Will the next generation of blockbuster therapies be won by science alone or by the speed of manufacturing execution?

50 The manufacturing executive’s new shield: closing the records liability gap

As regulators increasingly focus on individual accountability, can manufacturing leaders afford to treat data governance as a back-office function?

Digital

52 Reinventing cell therapy manufacturing with microfluidics: from cure to care

As more and more cell therapies move from experimental treatments to commercial realities, manufacturing remains the primary bottleneck to patient access.

55 Getting AI right in drug discovery: why data quality is a scientific integrity issue

Every artificial intelligence-assisted conclusion that makes it outside the walls of an R&D organisation is a scientific claim that eventually has to stand on its own.

Lab Design

58 From variability to predictability: redefining visual inspection in high-mix pharma manufacturing

In high-mix environments, inspection systems must first be flexible – everything else builds on that foundation.

62 Silence and noise: twin threats to scientific resilience in biopharma R&D

As workforce turnover reshapes the industry, how can organisations preserve the knowledge that drives scientific progress?

Regulars

5 Editor's Desk

Our interrim editor discusses the wonderful contributions that IPT Summer has to offer.

6 Product News

IPT highlights some of the most recent exciting advancements in pharmaceutical manufacturing.

66 Events

A collation of the top Pharma events for Summer 2026!

Index of Advertisers

IFC CARBOGEN AMCIS IBC PPMA 2026

49 CPHI Milan OBC BIO-Europe Supplement