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Manufacturing

Innovations in pharmaceutical Manufacturing Including Capsuling, Tabletting, Additive Manufacturing, Biomanufacturing Operations

Articles

The six keys to client satisfaction in biologics CDMO services
The six keys to client satisfaction in biologics CDMO services

This article explores the significant opportunities within the biologics contract development and manufacturing organisation (CDMO) industry to optimize client satisfaction by meeting the critical demands of discerning clients. Six key facets are identified as pivotal to success, while underscoring the fundamental role of a client-centric approach and the importance of building and nurturing strong client relationships.

18 March 2024Manufacturing
Why manufacturers can rely on robots to bridge efficiency gaps and streamline processes
Why manufacturers can rely on robots to bridge efficiency gaps and streamline processes

Robots are revolutionising manufacturing, but manual programming hampers their potential. Robot offline programming offers a digital solution, reducing human work hours by up to 80% and ensuring swift task readiness

18 March 2024Manufacturing
The early screening imperative: the key role of in vitro diagnostic products
The early screening imperative: the key role of in vitro diagnostic products

In the post-covid-19 era, healthcare grapples with staff shortages and treatment delays, emphasising the need for early diagnosis. While regulatory changes pose challenges, eu extensions provide relief

18 March 2024Manufacturing
Peptide therapeutics: reconstructing protein surfaces using constrained peptides
Peptide therapeutics: reconstructing protein surfaces using constrained peptides

Proteins govern crucial biological processes, making protein-protein interactions vital for understanding and treating diseases, peptide-based mimics offer tailored therapeutic approaches, yet optimising their efficacy poses challenges

18 March 2024Manufacturing
Multi-particulate formulations: the power of many
Multi-particulate formulations: the power of many

After assessing the various routes of drug administration, oral delivery stands out as the safest and, as a result, the most universally accepted among patients. Single-unit dosage forms, including tablets followed by capsules, have been identified as the preferred designs for immediate or modified release formulations

20 December 2023Manufacturing
Inhaled medicines and particle size analysis
Inhaled medicines and particle size analysis

Drug administration by inhalation is an established technique for treating respiratory and systemic diseases. Effective drug delivery to the lungs requires the aerosolisation and dispersion of a formulation into particles or droplets in the inhalable size range, typically an aerodynamic diameter below 5 µm. In many cases, particle engineering is used to optimise a formulation for efficacy

20 December 2023Manufacturing
Addressing bottlenecks in AAV analysis for efficient manufacturing
Addressing bottlenecks in AAV analysis for efficient manufacturing

Refeyn discusses the challenges associated with AAV manufacture, the key analytical techniques currently used to facilitate insight into AAV samples and novel techniques striving to overcome current limitations

20 December 2023Manufacturing
Balancing the evolution of MES with traditional methodologies
Balancing the evolution of MES with traditional methodologies

By seamlessly integrating a dynamic MES into digitisation road maps, companies have achieved greater operational efficiency, data integrity and harnessed real-time insights to meet their strategic goals

20 December 2023Manufacturing
Natoli Engineering, an industry leader in tablet and encapsulation success
Natoli Engineering, an industry leader in tablet and encapsulation success

Natoli engineering has made significant contributions to the pharmaceutical and nutraceutical industries. Specialising in tablet compression and encapsulation technology, innovative machines, tooling and solutions that enhance tablet and encapsulation manufacturing processes, Natoli has advanced manufacturing technologies and practices worldwide

24 September 2023Manufacturing
The microneedle’s edge: growth and opportunity in emerging technology
The microneedle’s edge: growth and opportunity in emerging technology

While the drug-device combination product industry is always investing in technology that could better meet the needs of patients, governments and sponsors, the COVID-19 pandemic has accelerated the process, bringing in more outside investment and a broader range of organisations in active development

24 September 2023Manufacturing
mRNA therapeutics: development and manufacturing trends in a rapidly evolving space
mRNA therapeutics: development and manufacturing trends in a rapidly evolving space

What are some trends in the mRNA space surrounding the growing desire for speed-to-market, and what hurdles are impeding the achievement of this goal?

24 September 2023Manufacturing
Integrated development strategies for drug product optimisation
Integrated development strategies for drug product optimisation

Drug product optimisation, also known as reformulation, is a development step required by all drugs en route to market. This process takes a long time, carries a considerable cost and places significant emphasis on the predictive power of laboratory and preclinical assessments. What are some alternative pathways available to development teams?

24 September 2023Manufacturing