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Discovery and Development

Innovations in pharmaceutical Discovery and Development Including Bioinformatics, Proteomics, Nanotechnology, Formulation and Recipients, Extractables and Leachables

Articles

Non-viral gene therapies: GETting growth-factor-based healing right in orthopaedics
Non-viral gene therapies: GETting growth-factor-based healing right in orthopaedics

The development and use of novel gene therapy approaches is increasing. With the advent of innovative technologies using improved tropism and safer viral-based systems, and nanotechnology advancing non-viral delivery of nucleic acid vectors, there will be more gene-based products entering the market in near future

18 March 2024Discovery and Development
Advancements in preclinical imaging: a look into the future of drug development
Advancements in preclinical imaging: a look into the future of drug development

Ipt talks with jacob tesdorpf at revvity about the recent developments in preclinical imaging, from ai-enchanced analysis to refined disease models

18 March 2024Discovery and Development
Novel biosensors for enhanced antimicrobial delivery efficiency
Novel biosensors for enhanced antimicrobial delivery efficiency

The World Health Organization (WHO) has recognised the scarcity of new antimicrobial agents in the clinical pipeline. The prevailing approach to combatting antimicrobial resistance cannot solely rely on developing new drugs. Instead, we must seek ways to better understand and more efficiently use the drugs already at our disposal.

20 December 2023Discovery and Development
Mass spectrometry and proteomics: leading the charge in drug development
Mass spectrometry and proteomics: leading the charge in drug development

IPT talks to Oliver Rinner of Biognosys about Bruker’s recent majority investment in the business and how this, along with its own developments, will affect the future of proteomics research

24 September 2023Discovery and Development
High-throughput targeted metabolomics: the next generation
High-throughput targeted metabolomics: the next generation

With its potential to transform various industries and fields of research − including pharmaceuticals, preventive healthcare, agriculture and food safety − metabolomics is a rapidly growing field that has the potential to revolutionise our understanding of biological systems and disease mechanisms

24 September 2023Discovery and Development
AI in the Drug Discovery Industry
AI in the Drug Discovery Industry

IPT talks to Tamsin Mansley of Optibrium about how AI has been used in drug discovery up until now, and how it can be best applied in the future

3 April 2023Discovery and Development
Coding of Cell Identity
Coding of Cell Identity

Non-human cells have been used in drug discovery for years. How are novel technologies helping researchers to move past this method?

3 April 2023Discovery and Development
Five Factors Driving Cell and Gene Therapy Developers Towards Gammaretrovirus
Five Factors Driving Cell and Gene Therapy Developers Towards Gammaretrovirus

What has led to the rising trend for Cell & Gene Therapy (CGT) developers to choose retroviral vectors over other potential vectors, and what are the many drivers behind this selection process?

14 December 2022Discovery and Development
Collaboration and Centralisation: The Key to Successful Drug Development
Collaboration and Centralisation: The Key to Successful Drug Development

IPT talks to Dr Fiona McLaughlin and Neil Bell of Avacta Therapeutics about the need for cohesion when researching and developing a new drug between life science companies, academia, and medical practitioners

14 December 2022Discovery and Development
The Pioneering Tech Speeding Up Drug Development
The Pioneering Tech Speeding Up Drug Development

IPT talks to Johannes Stanta at Celerion about how improvements in molecular and cellular capabilities are aiding Good Laboratory Practice/Good Clinical Practice (GLP/GCP) standards

14 December 2022Discovery and Development
An Alternative Regulatory Pathway for Generic Orally Inhaled Drug Products
An Alternative Regulatory Pathway for Generic Orally Inhaled Drug Products

The in vitro-in silico ‘alternative’ bioequivalence pathway for generic inhaled drug products, and how to factor in patient variability to successfully replace your comparative clinical end-point study

14 December 2022Discovery and Development
People, Pipelines, and Projections: Helping Emerging Therapeutics Get to Market Efficiently
People, Pipelines, and Projections: Helping Emerging Therapeutics Get to Market Efficiently

From tools and assays, to the need for improved collaboration, the potential answers to this question are numerous. IPT asked representatives from DeciBio, Cybin, and GORE PharmBIO for their opinions

9 October 2022Discovery and Development