IPT Winter 2022 - Contents

CONTENTS

WINTER 2022

Analytics

6. Cell Phenotyping and Functional Measurements Using Flow Cytometry

What’s driving demand for flow cytometry, and what barriers and breakthroughs can be expected in the future?

8. Raman Analysers Take Centre Stage to Streamline Pharmaceutical Quality Control

How are handheld Raman devices and process analysers, implementing Raman spectroscopy, streamlining Quality Control and enabling continuous manufacturing.

Discovery & Development

12. Five Factors Driving Cell and Gene Therapy Developers Towards Gammaretrovirus

What has led to the rising trend of cell & gene therapy developers consistently choosing retroviral vectors over other potential vectors – what are the factors driving this decision?

16. Collaboration and Centralisation: The Key to Successful Drug Development

IPT talks to Fiona McLaughlin and Neil Bell of Avacta Therapeutics about the need for cohesion when researching and developing a new drug between life science companies, academia, and medical practitioners.

20. The Pioneering Tech Speeding Up Drug Development

Johannes Stanta of Celerion speaks to IPT about research into molecular and cellular capabilities, and how they are improving Good Laboratory Practice/Good Clinical Practice (GLP/GCP) standards.

22. DEL, AI, and ML: The Digital Future of Research Tools

IPT talks to Noor Shaker about how digital technology
such as DNA-Encoded Libraries, AI, and machine
learning, can aid research.

24. Turning an Ocean of Data into Actionable Wisdom to Support Optimal Site Identification

Can AI help researchers when finding the best sites for their clinical trials by utilising Big Data?

26. The Burden of Proof – Implementing Blockchain in Life Sciences

Why are more pharma companies choosing to implement blockchain technology when improving data collection and protection?

30. Digitalisation – A Giant Step Towards Global
Access to Medicine

How will the mass integration of digital tech help the
most underserved countries?

Manufacturing

34. Error Mitigation in Pharmaceutical Quality Assurance and Quality Control

How can the pharma industry ensure quality assurance and control throughout the manufacturing process?

38. An Alternative Regulatory Pathway for Generic Orally Inhaled Drug Products

Looking at in-vitro-in silico as an ‘alternative’ pathway for generic inhaled drug products, and how companies should factor in patient variability.

43. Managing the Complex Regulatory Pathways for
Bioprinting Breakthroughs

As bioprinting becomes more and more common in the
pharma industry, developers need to better understand regulatory classification.

Regulars

5. Editorial Desk

Rounding off 2022 with a reflection on a year of exciting developments in pharmaceutical tech.

46. Events Index

The IPT editorial team looks forward to the best events in the first quarter of 2023.

Index of Advertisers

IFC. ICON

11. PharmaRole

19. IPT Online

29. International Clinical Researcher of the Year Awards

IBC. Samedan Magazines

OBC. Natoli Engineering Company Inc.

EXECUTIVE DIRECTOR
PMGroup Worldwide Ltd
Karl Equi

GROUP MANAGING EDITOR
Iona Everson

EDITORIAL ASSISTANTS
James Spargo
Betsy Goodfellow

EDITORIAL AND PRODUCTION ASSISTANT
Charlie Blackie-Kelly

SALES
Helga Schweissguth

DESIGN
Peter May

FRONT COVER
PopTika – Shutterstock.com

DIGITAL EDITION
by Calaméo
www.calameo.com

CONTACT US
Tel: +44 (0)20 7724 3456
Fax: +44 (0)20 7403 7747

PRINTING
Hardings Print Solutions
www.hps-ltd.org.uk

SUBSCRIPTIONS AND DATA
Curwood CMS Ltd
Unit 9 Barns & Stables, Timworth Green,
IP31 1HS
c-cms.com
Tel: 01580 883841
Email: enquiries@c-cms.com
www.iptonline.com

Innovations in Pharmaceutical Technology (ISSN: 1471-7204, USPS No: 025082) is published four times a year – March, June, September, and December – by Samedan Ltd.

The opinions and views expressed by the authors in this book are not necessarily those of the Editor the Publisher and, while every care has been taken in the preparation of the book, the Editor and the Publisher are not responsible for such opinions and views or for
any inaccuracies in the articles.

The Publisher is not responsible for any images supplied by contributors. While every care is taken with artwork supplied, the Publisher cannot be held responsible for any loss or damage incurred.

The entire content of this publication is protected by copyright. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form, by any means – electronic,
mechanical, photocopying, or otherwise – without the prior permission of the Publisher.

© 2022 Samedan Ltd
Pharmaceutical Publishers

Human-Centred Design: From Inception to Integration

IPT sat down with Dr Chris Vincent at PDD, to understand more about the digital innovations that are leading design and whether technologies like Extended Reality (XR) can be beneficial to the process

Dec 14, 2022

The Importance of Temperature Control in Pharmaceutical Analysis

As technology within the analysis sphere continues to evolve, temperature control is becoming increasingly important for drug discovery and research

Dec 14, 2022

Providing Support Throughout the Patient Journey

Concierge services are critical to helping patients navigate technology and other logistics in a decentralised clinical trial. How best can they be implemented?

Dec 14, 2022

Human-Centred Design: From Inception to Integration

The Importance of Temperature Control in Pharmaceutical Analysis

Providing Support Throughout the Patient Journey

Innovations in Pharmaceutical Technology (IPT)

Categories

Social Footprints